globaltbprogramconceptThe Global Childhood TB Program began in 2011 with the recruitment of world renown pediatric TB expert Dr. Anna Mandalakas to Baylor College of Medicine and Texas Children’s Hospital in Houston, TX. As Director of the Global Childhood TB program, Dr. Mandalakas was commissioned by the World Health Organization (WHO) to perform an expert review of the diagnostic tool, geneXpert to inform policy making on childhood TB diagnostics.

The mission of The Global Tuberculosis (TB) Program is well aligned with the World Health Organization (WHO) Millenium Development Goals and uses the tools of research, education, and advocacy to prevent, diagnose, and treat tuberculosis in children. The long-term goal of our program is the establishment of a network of Childhood Tuberculosis Centers of Excellence built upon Texas Children’s existing clinical infrastructure in Sub-Saharan Africa. Our Global Childhood TB Program team works in four inter-related areas including disease prevention, diagnostics, treatment, and immunology. These program domains are built upon a data collection core and complemented by rigorous epidemiological and operational research.

The Global Childhood TB Program uses partnerships with other members of the Baylor College of Medicine family and collaborators at other institutions to develop effective, sustainable, standardized methods of diagnosing tuberculosis in children and is attempting to identify biomarkers correlating with progression from tuberculosis infection to disease, as well as standardizing screening processes to better characterize epidemiological risk factors for tuberculosis.